Quercetin has antioxidant and anti-inflammatory effects which might help reduce inflammation, kill cancer cells, control blood sugar, and help prevent heart disease.
This clip is taken from the Joe Rogan Experience #1589 with Dr. Mark Gordon, the only person during this entire pandemic who has given supplement advice clearly on a mainstream show. Mainstream media still hasn’t mentioned how to boost immunity or preventative protocol for Covid-19.
Complete list of supplements/vitamins mentioned: -
Zinc (15mg x2 a day preventative, change to 30mg x2 if you have covid) -
Quercetin (500mg x2 a day preventative, change to 1000mg x2 if you have covid).
Also, green tea and turmeric can be good sources but I think they are far lower (eg green tea infusions only have 2.1 mg quercetin 100 mL−1)
Vitamins (doctor recommended getting your levels measured first. If you have enough, taking more won't give you benefits but might be harmful)
Vitamin C (Ascorbyl palmitate version)
Vitamin D3 (studies have found at most 1 in 5 people are deficient. Doctor takes 120,000IU a week)
Vitamin E - DHEA (start at 25mg at night time)
Pregnenolone (100mg after dinner)
Fish oil
Exercise
What are the benefits of Quercetin?
Quercetin has antioxidant and anti-inflammatory effects which might help reduce inflammation, kill cancer cells, control blood sugar, and help prevent heart disease.
Cytokines are a large group of proteins, peptides or glycoproteins that are secreted by specific cells of immune system. Cytokines are a category of signaling molecules that mediate and regulate immunity, inflammation and hematopoiesis (is the process through which the body manufactures blood cells).
What is zinc?
Zinc is an essential dietary mineral that has numerous roles in the body, most notably as a catalytic and structural element in hundreds of metalloproteins. Meat, egg, and legume products are common sources. Oysters are particularly good sources of zinc.
What are zinc’s benefits?
Any benefits of oral zinc supplements or increased dietary intake will depend on the zinc status of the individual. Some research suggests that when zinc levels are low, insulin sensitivity and testosterone can decrease, and supplementation can bring levels closer to normal.
Zinc lozenges, in high doses, seem to reduce the duration of common colds, though it's unclear if they reduce the risk of getting colds in the first place or the severity of symptoms. Their effects are largely limited to throat and nasal symptoms, and high doses tend to come with some mild but notable side-effects like nausea and metallic taste in the mouth.
Other areas of note are depression and acne, which can frequently benefit from increased zinc intake if levels are low.
Zinc is lost through sweat, making supplementation very important for athletes that don’t get a lot of zinc through food. Insulin resistance can also decrease zinc levels.
What are zinc’s side effects and drawbacks?
Large doses of zinc can produce nausea and other forms of gastrointestinal upset, particularly when taken on an empty stomach. Large doses of zinc can also cause a copper deficiency and lead to overdose.
What problems does a zinc deficiency cause?
Zinc deficiency in childhood can impair growth. In adults, zinc deficiency can result in hypogonadism in men, as well as mental lethargy, depression, and skin abnormalities. Low levels of zinc due to diabetes can further worsen insulin resistance. It is estimated that inadequate zinc intake affects around 10% of persons in the US, but global insufficiency rates are over 50%.
What are the benefits of Testosterone?
CD8+ (cytotoxic) T cells, like CD4+ Helper T cells, are generated in the thymus and express the T-cell receptor. However, rather than the CD4 molecule, cytotoxic T cells express a dimeric co-receptor, CD8, usually composed of one CD8α and one CD8β chain.
Interleukin 10 (IL-10) is a cytokine with potent anti-inflammatory properties that plays a central role in limiting host immune response to pathogens, thereby preventing damage to the host and maintaining normal tissue homeostasis. Dysregulation of IL-10 is associated with enhanced immunopathology in response to infection as well as increased risk for development of many autoimmune diseases. Thus a fundamental understanding of IL-10 gene expression is critical for our comprehension of disease progression and resolution of host inflammatory response. In this review, we discuss modes of regulation of IL-10 gene expression in immune effector cell types, including signal transduction, epigenetics, promoter architecture, and post-transcriptional regulation, and how aberrant regulation contributes to immunopathology and disease progression.
Quercetin has antioxidant and anti-inflammatory effects which might help reduce inflammation, kill cancer cells, control blood sugar, and help prevent heart disease.
In preliminary human studies, oral intake of quercetin in doses up to one gram per day over three months did not cause adverse effects.
Benefits of Quercetin
Drops the inflammatory Cytokines.
Increases Mitochondria
Mitochondria are membrane-bound cell organelles (mitochondrion, singular) that generate most of the chemical energy needed to power the cell's biochemical reactions.
Chemical energy produced by the mitochondria is stored in a small molecule called adenosine triphosphate (ATP)
What are the benefits of Zinc 15/30mg twice a day
What is zinc?
Zinc is an essential dietary mineral that has numerous roles in the body, most notably as a catalytic and structural element in hundreds of metalloproteins. Meat, egg, and legume products are common sources. Oysters are particularly good sources of zinc.
What are zinc’s benefits?
Any benefits of oral zinc supplements or increased dietary intake will depend on the zinc status of the individual. Some research suggests that when zinc levels are low, insulin sensitivity and testosterone can decrease, and supplementation can bring levels closer to normal.
Zinc lozenges, in high doses, seem to reduce the duration of common colds, though it's unclear if they reduce the risk of getting colds in the first place or the severity of symptoms. Their effects are largely limited to throat and nasal symptoms, and high doses tend to come with some mild but notable side-effects like nausea and metallic taste in the mouth.
Other areas of note are depression and acne, which can frequently benefit from increased zinc intake if levels are low.
Zinc is lost through sweat, making supplementation very important for athletes that don’t get a lot of zinc through food. Insulin resistance can also decrease zinc levels.
What are zinc’s side effects and drawbacks?
Large doses of zinc can produce nausea and other forms of gastrointestinal upset, particularly when taken on an empty stomach. Large doses of zinc can also cause a copper deficiency and lead to overdose.
Many supplements use far more than the RDA, and a combination of supplements, fortified foods, and high zinc foods may lead to exceeding the tolerable upper intake level for adults, which is 40 mg per day. High dose zinc lozenges can lead to nausea and a metallic taste in the mouth, and should only be taken for a short time, if at all.
What problems does a zinc deficiency cause?
Zinc deficiency in childhood can impair growth. In adults, zinc deficiency can result in hypogonadism in men, as well as mental lethargy, depression, and skin abnormalities. Low levels of zinc due to diabetes can further worsen insulin resistance. It is estimated that inadequate zinc intake affects around 10% of persons in the US, but global insufficiency rates are over 50%.
What are the benefits of Testosterone?
Testosterone is a hormone found in humans, as well as in other animals. In men, the testicles primarily make testosterone. Women’s ovaries also make testosterone, though in much smaller amounts.
The production of testosterone starts to increase significantly during puberty and begins to dip after age 30 or so.
Testosterone is most often associated with sex drive and plays a vital role in sperm production. It also affects bone and muscle mass, the way men store fat in the body, and even red blood cell production.
A man’s testosterone levels can also affect his mood.
Low levels of testosterone, also called low T levels, can produce a variety of symptoms in men, including:
The production of testosterone starts to increase significantly during puberty and begins to dip after age 30 or so.
Testosterone is most often associated with sex drive and plays a vital role in sperm production. It also affects bone and muscle mass, the way men store fat in the body, and even red blood cell production.
A man’s testosterone levels can also affect his mood.
Low levels of testosterone, also called low T levels, can produce a variety of symptoms in men, including:
decreased sex drive
less energy
weight gain
feelings of depression
moodiness
low self-esteem
less body hair
thinner bones
While testosterone production naturally tapers off as a man ages, other factors can cause hormone levels to drop. Injury to the testicles and cancer treatments such as chemotherapy or radiation can negatively affect testosterone production.
Chronic health conditions and stress can also reduce testosterone production. Some of these include:
AIDS
kidney disease
alcoholism
cirrhosis of the liver
Testosterone levels decline steadily in adult women, however, low T levels can also produce a variety of symptoms, including:
low libido
reduced bone strength
poor concentration
depression
Low T levels in women can be caused by removal of the ovaries as well as diseases of the pituitary, hypothalamus, or adrenal glands.
Testosterone therapy may be prescribed for women with low T levels, however, the treatment’s effectiveness on improving sexual function or cognitive function among postmenopausal women is unclear.
less energy
weight gain
feelings of depression
moodiness
low self-esteem
less body hair
thinner bones
While testosterone production naturally tapers off as a man ages, other factors can cause hormone levels to drop. Injury to the testicles and cancer treatments such as chemotherapy or radiation can negatively affect testosterone production.
Chronic health conditions and stress can also reduce testosterone production. Some of these include:
AIDS
kidney disease
alcoholism
cirrhosis of the liver
Testosterone levels decline steadily in adult women, however, low T levels can also produce a variety of symptoms, including:
low libido
reduced bone strength
poor concentration
depression
Low T levels in women can be caused by removal of the ovaries as well as diseases of the pituitary, hypothalamus, or adrenal glands.
Testosterone therapy may be prescribed for women with low T levels, however, the treatment’s effectiveness on improving sexual function or cognitive function among postmenopausal women is unclear.
CD8+ (cytotoxic) T cells, like CD4+ Helper T cells, are generated in the thymus and express the T-cell receptor. However, rather than the CD4 molecule, cytotoxic T cells express a dimeric co-receptor, CD8, usually composed of one CD8α and one CD8β chain.
Interleukin 10 (IL-10) is a cytokine with potent anti-inflammatory properties that plays a central role in limiting host immune response to pathogens, thereby preventing damage to the host and maintaining normal tissue homeostasis. Dysregulation of IL-10 is associated with enhanced immunopathology in response to infection as well as increased risk for development of many autoimmune diseases. Thus a fundamental understanding of IL-10 gene expression is critical for our comprehension of disease progression and resolution of host inflammatory response. In this review, we discuss modes of regulation of IL-10 gene expression in immune effector cell types, including signal transduction, epigenetics, promoter architecture, and post-transcriptional regulation, and how aberrant regulation contributes to immunopathology and disease progression.
Vitamin D3 offers many health benefits. It is known to help strengthen bones and muscles, boost immunity, increase mood, aid in weight loss, and improve heart function.
Vitamin E helps maintain healthy skin and eyes, and strengthen the body's natural defence against illness and infection (the immune system).
Pregnenolone is a steroid hormone that plays a key role in the production of other steroid hormones, including progesterone, DHEA, and estrogen. The substance is found naturally in the body, but some people also take it in supplement form to help keep memory sharp through the years.
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